A truly transformative functional mushroom formula—not merely a blend. At the heart of Twelve Rivers is an artful—and masterful—formulation of expertise, precision, and purposeful crafting.
Developed by our clinical master herbalists, Twelve Rivers offers a comprehensive daily functional mushroom tonic, providing adaptogenic support, immune resilience, and holistic functional nutrition for total well-being.*
Twelve Rivers MycoMedic Extract Powder Elixir is an integrative formulation of standardized whole fruiting body mushroom extraction—Chaga, Reishi, Cordyceps, Turkey Tail, Maitake, Royal Sun Agaricus, Fú Shēn, and Willow Bracket.—into a single, full-spectrum and synergistic solution for promoting immune health, sustained vitality, and endocrine support.*
Twelve Rivers MycoMedic Extract Powder Elixir is a full-spectrum, synergistic formula integrating standardized whole fruiting body extracts of Chaga, Reishi, Cordyceps, Turkey Tail, Maitake, Royal Sun Agaricus, Fú Shēn, and Willow Bracket. Through a meticulous extraction process, Twelve Rivers unlocks the full potency of these bioactive compounds—including beta-glucans, polysaccharides, and terpenes—for optimal bioavailability and absorption, supporting immune health, sustained vitality, and endocrine function.*
Designed with intention and crafted with integrity and purpose, Twelve Rivers is your gateway to the true power of functional mushrooms—an expertly formulated, precisely extracted formula of Dàodì-sourced, whole fruiting body mushrooms for uncompromising quality and efficacy in every serving.*
The Twelve Rivers Functional Mushroom MycoMedic Elixir Extract Powder is a masterfully crafted adaptogenic tonic, uniting eight whole fruiting body mushrooms in a dual-stage extraction for full-spectrum support.* Developed for daily use, this formula provides a precise profile of immune resilience, metabolic support, and foundational vitality in a convenient, easy-to-use powder.*
Add Twelve Rivers to warm water, tea, or coffee to seamlessly integrate forest wisdom into your wellness routine—delivering uncompromising quality and true functional benefits in every serving.*
Field Notes
When we set out to create a truly transformative functional mushroom formula in 2013, we knew it had to be more than just a blend of effective ingredients—it had to be a purposefully crafted tonic that supports the body’s innate rhythms and resilience. After two years of development, Twelve Rivers was first released in February 2015, embodying our vision and drawing from time-honored Classical Chinese Medicine principles, precise formulation techniques, and the interconnected flow of Qì throughout the body.*
With the Twelve Rivers formula, we wanted to create something that aligns deeply with our philosophy of functional, holistic support. This formula is more than an adaptogen blend—it is a harmonized, full-spectrum tonic, integrating the best qualities of eight functional mushrooms to fortify immune defenses (Wèi Qì), nourish foundational vitality (Jīng), and sustain mental clarity and resilience (Shén).* Each mushroom is carefully selected not only for its individual properties but for how it complements the others, following the traditional Jūn-Chén-Zuǒ-Shǐ formulation strategy.* This ensures that the formula works in synergy—mirroring the body’s twelve meridians, or rivers, that sustain vitality and resilience.*
Behind the Twelve Rivers Name
The name Twelve Rivers is inspired by—and applies—Classical Chinese Medicine, where the body is understood as a landscape of Qì—the life force that sustains health and vitality. In this tradition, the twelve primary meridians, often likened to rivers, carry Qì throughout the body, nourishing every system and maintaining balance. This is the heart of the name Twelve Rivers.
The Twelve Rivers formula is designed to strengthen this flow by fortifying Wèi Qì (Defensive Energy) to support immune and mental resilience, nourishing Jīng (Essence) to sustain deep energy reserves and longevity, and harmonizing Shén (Spirit) to enhance clarity and emotional health.* By doing so, Twelve Rivers promotes both short-term vitality and long-term well-being.*
The Twelve Rivers formula is designed to strengthen this flow by fortifying Wèi Qì (Defensive Energy) to support immune and mental resilience, nourishing Jīng (Essence) to sustain deep energy reserves and longevity, and harmonizing Shén (Spirit) to enhance clarity and emotional health.* By doing so, Twelve Rivers promotes both short-term vitality and long-term well-being.*
Just as rivers shape landscapes over time, Twelve Rivers provides deep, ongoing support for foundational health, helping the body sustain strength, renewal, and adaptability in the face of daily challenges and the unique stressors of modernity.*
While deeply rooted in tradition, Twelve Rivers Extract Powder is crafted with a modern understanding—and designed for convenience. Expertly prepared and ready to use, no further extraction is needed to unlock its full spectrum of bioactive compounds—beta-glucans, polysaccharides, and terpenes. Simply add Twelve Rivers to warm water, tea, or coffee to create a nourishing ritual that effortlessly integrates forest wisdom into your daily routine.
Twelve Rivers Functional Mushroom MycoMedic Extract Powder Elixir is more than the sum of its parts. Designed for those who understand the value of sourcing, tradition, and expert formulation, Twelve Rivers is a precisely crafted formula that fortifies immunity, sustains vitality, and supports the balanced flow of Qì for lasting resilience.
Twelve Rivers is your invitation to discover forest wisdom and the infinite power within. Welcome to the trail family.
The Twelve Rivers Functional Mushroom MycoMedic Elixir is masterfully designed to support the body’s twelve primary Qì meridians—the vital pathways through which life force flows.
Rooted in Classical Chinese Medicine (CCM) and developed using the Jūn-Chén-Zuǒ-Shǐ framework, Twelve Rivers harnesses the synergy of eight functional mushrooms to fortify Wèi Qì (Defensive Energy), nourish Jīng (Essence), regulate Qì circulation, and balance Yīn and Yáng while harmonizing Shén (Spirit)—promoting resilience, immune function, and mental clarity.*
Every ingredient in Twelve Rivers is selected with purpose and intention, each playing a deliberate role in supporting specific organ systems and energetic pathways:
Turkey Tail and Royal Sun Agaricus reinforce the body's first line of defense, supporting immune adaptability and protecting against external influences that challenge well-being.*
Chaga and Willow Bracket deeply nourish Kidney Yīn, replenishing foundational energy reserves and sustaining long-term vitality and resilience.* By supporting Jīng, this formula promotes longevity and strengthens the body’s ability to recover from stress and exertion.*
Cordyceps and Maitake invigorate Qì flow, supporting stamina, lung function, and metabolic efficiency—ensuring smooth, balanced energy circulation throughout the body’s twelve meridians. This formula also helps maintain Yīn-Yáng harmony, preventing imbalance and depletion over time.*
Maitake strengthens the Spleen and Stomach meridians, enhancing digestion and nutrient assimilation, which are essential for overall energy production and well-being.*
Reishi and Fú Shēn help stabilize and calm Shén, supporting emotional balance, cognitive resilience, and overall mental well-being. This promotes a sense of grounding, clarity, and adaptability in the face of stress.*
By working across all twelve meridians, Twelve Rivers delivers a full-spectrum, synergistic approach to functional mushroom support—sustaining both physical endurance and cognitive clarity.*
Designed as a true adaptogenic tonic, Twelve Rivers supports the body’s ability to adapt to stressors, promoting immune resilience, energy levels, and long-term wellness.* Whether used daily or in times of acute illness, Twelve Rivers seamlessly bridges classical herbal wisdom and modern phytotherapy, offering a foundation for lasting health and balance.*
Reishi – 12.5% of Formula
Description: Reishi, known as Líng Zhī in Classical Chinese Medicine (CCM), is one of the most revered medicinal mushrooms, often called the "Mushroom of Immortality." Traditionally, Reishi has been used to nourish the Heart, calm the Shén (spirit), and support the Liver and Lung channels. Within herbal medicine, Reishi is known for its role in promoting resilience, fostering emotional equilibrium, and supporting immune function.*
As a Qi- and Shén-nourishing adaptogen, Reishi is valued for its ability to moderate the body’s response to stress, encourage deep, restorative calm, and promote long-term vitality. It is widely regarded as a premier longevity tonic in both classical and modern herbalism.*
Ethnobotanical Tradition: First recorded in Shén Nóng Běn Cǎo Jīng (ca. 200 CE) and later detailed in Běncǎo Gāngmù (1578), Reishi has been revered in China, Japan, and Korea for its association with longevity and spiritual cultivation.
Classified as a Superior Herb in the Shén Nóng Běn Cǎo Jīng, Reishi was traditionally reserved for royalty and Daoist practitioners, its rarity in the wild making it a symbol of enlightenment. Historical texts describe its ability to harmonize mind, body, and spirit, supporting both physical and Shén (spiritual) well-being.*
Sourcing: Our Reishi is organically cultivated on Duanwood logs in Asia—replicating its natural growing environment to yield the highest concentration of bioactive compounds. Duanwood cultivation enhances Reishi’s potency, ensuring it develops its full spectrum of polysaccharides, triterpenes, and beta-glucans.*
Parts Used: Fruiting Body
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Role in Formula: As the Jūn Yào (Principal Herb), Reishi serves as the guiding force of the Twelve Rivers formula, setting the foundation for its adaptogenic and immune-supportive effects. It harmonizes Qi, nourishes Shén, and provides broad-spectrum support for stress response, emotional well-being, and immune resilience. Its role in the formula is both foundational and expansive—providing the depth of support upon which the entire formulation is built.*
Cordyceps – 12.5% of Formula
Description: Cordyceps, known as Dōng Chóng Xià Cǎo in Classical Chinese Medicine (CCM), is a renowned tonic used to invigorate the Lung and Kidney channels. It is traditionally regarded for its ability to support both Yīn and Yáng energies, contributing to sustained stamina, respiratory function, and overall vitality.*
Beyond its historical use as a foundational tonic, Cordyceps is valued for its role in supporting Wèi Qì (defensive energy), which governs immune resilience and adaptive response to stress. It is an essential herb for those seeking to strengthen endurance, promote deep energy reserves, and maintain longevity.*
Ethnobotanical Tradition: First recorded in the Táng Běncǎo (659 CE) and later expanded upon in the Běncǎo Gāngmù (1578), Cordyceps has been valued in Tibetan and Chinese medicine for centuries. While Cordyceps sinensis(the rare, wild species) was historically prized for its ability to enhance stamina, lung function, and endurance, Cordyceps militaris has emerged as a more sustainable and potent alternative with similar therapeutic properties.
Once reserved for the imperial court due to its rarity, traditional texts describe Cordyceps as a tonic for fortifying the body, supporting Wei Qi (defensive energy), and promoting long-term vitality.*
Sourcing: Our Cordyceps is certified organically cultivated in Aisia in a controlled environment designed to closely replicate its natural habitat. This method ensures a consistent, high-quality source of bioactive compounds, including cordycepin and adenosine, which contribute to its adaptogenic and tonic properties.*
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Fruiting Body
Role in Formula: As the Chén Yào (Deputy Herb), Cordyceps works in synergy with the principal herb, Reishi, to fortify both immediate and long-term energy reserves. It strengthens Lung Yīn and Kidney Yáng while supporting endurance, respiratory function, and mental clarity. Within the Twelve Rivers formula, Cordyceps plays a vital role in sustaining resilience, promoting vitality, and enhancing physical and cognitive performance.*
Maitake / Hen-of-the-Woods (Grifola frondosa) – 12.5% of Formula
Description: Maitake, commonly called Hen-of-the-Woods in the West, is known as Huī Shù Huā in Chinese medicine and Maitake in Japanese. Celebrated in both Eastern and Western herbal traditions, Maitake is highly regarded for its ability to support immune function and help maintain healthy blood sugar levels.*
In Classical Chinese Medicine (CCM), Maitake is traditionally used to strengthen the Spleen and Stomach, enhancing the body’s capacity for nutrient assimilation and metabolic regulation. Recognized for its grounding properties, Maitake is believed to help stabilize the internal environment, contributing to overall well-being.*
Ethnobotanical Tradition: Maitake has been valued in Japanese and Chinese medicine for centuries, esteemed for its rich nutritional and tonic properties.*
Sourcing: Organically cultivated in Asia, our Maitake is carefully selected to preserve its natural balance of nutrients and bioactive compounds.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Fruiting Body
Role in Formula: As a Chén Yào (Deputy Herb), Maitake supports the Spleen and Stomach, aiding digestion and nutrient absorption while working synergistically with other herbs in the formula. Its role in promoting metabolic stability and immune resilience enhances the overall effectiveness of Twelve Rivers.*
Chaga (Inonotus obliquus) – 12.5% of Formula
Description: Chaga, known as Чага (Tschaga) in Russian and Bái Huà Róng in Chinese medicine, is a highly valued mushroom recognized for its rich nutritional profile and high antioxidant content. Revered in both Siberian folk medicine and Classical Chinese Medicine (CCM), Chaga is traditionally used to nourish and stabilize Kidney Yīn, supporting the body’s deep reserves of vitality.*
Chaga is particularly esteemed for its role in fortifying Kidney Yīn and Jīng—two essential foundations of longevity and resilience in CCM. Contemporary research highlights its potential in supporting immune function and promoting a healthy inflammatory response, reinforcing its status as a powerful adaptogen.*
Ethnobotanical Tradition: With a long history of use in Siberian folk medicine, Chaga has also been incorporated into CCM and other traditional systems for its deeply nourishing and restorative properties.*
Sourcing: Certified organic and wild-harvested in Arctic Siberia, our Chaga is carefully selected for its potency and collected in its natural habitat to preserve its Yīn-nourishing qualities.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Fruiting Body
Role in Formula: As a Zuǒ Yào (Assistant) Herb, Chaga enhances the actions of other ingredients in the formula. It supports overall vitality by tonifying Kidney Yīn and reinforcing Jīng, while synergistically boosting immune resilience, promoting stress adaptation, and providing deep systemic nourishment—key elements in Twelve Rivers’ comprehensive approach to health.*
Fú Shén (Wolfiporia extensa) – 12.5% of Formula
Description: Fú Shén is a highly regarded herb in Classical Chinese Medicine (CCM), traditionally used to calm the Shén (spirit) and strengthen the Heart (Xīn) and Spleen (Pí). Known for its grounding and stabilizing properties, it is frequently used to support emotional well-being, mental clarity, and digestive health—three closely linked functions in CCM.*
Fú Shén is particularly valued for its ability to anchor the Hún (ethereal soul), making it an important herb for restoring emotional stability, soothing restlessness, and promoting a sense of centeredness. It has been historically used to ease occasional worry and tension while supporting the body's ability to adapt to stress.*
Ethnobotanical Tradition: Cherished in Chinese herbal medicine, Fú Shén has long been used in formulas designed to calm the mind, nourish the Heart, and strengthen the digestive system—a reflection of the deep interconnection between emotional and physical well-being in CCM.*
Sourcing: Organically cultivated in Asia, our Fú Shén is sourced using traditional methods to preserve its calming and grounding qualities.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Sclerotium (Skin)
Role in Formula: As a Zuǒ Yào (Assistant) Herb, Fú Shén enhances the formula’s ability to soothe the mind, regulate the Heart and Spleen, and promote emotional balance. Its role in stabilizing Shén, supporting digestive resilience, and fostering mental clarity makes it a crucial part of Twelve Rivers’ comprehensive approach to wellness.*
Royal Sun Agaricus / Royal Sun Blazei (Agaricus blazei Murill) – 12.5% of Formula
Description: Known as Jī Sōng Róng in Classical Chinese Medicine (CCM), Royal Sun Agaricus is valued for its immune-supportive and detoxifying properties. Traditionally associated with the Lung (Fèi) and Liver (Gān) channels, it is believed to strengthen the body's natural defenses, promote detoxification, and support metabolic health.
Royal Sun Agaricus has also been regarded for its role in supporting overall vitality and longevity—a reflection of its deep nutritional and medicinal properties.*
Ethnobotanical Tradition: Originally native to Brazil, Royal Sun Agaricus, known locally as "Cogumelo do Sol" (Mushroom of the Sun), has been cherished by indigenous communities for its ability to enhance vitality and promote long-term wellness. Its integration into Chinese herbalism and other traditional medicine systems speaks to its broad-ranging benefits and adaptability.*
Sourcing: Organically cultivated in Asia, our Royal Sun Agaricus is grown using practices that preserve its full spectrum of bioactive compounds, ensuring its high nutritional and therapeutic value.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Whole Mushroom
Role in Formula: As a Zuǒ Yào (Assistant) Herb, Royal Sun Agaricus supports immune resilience, aids detoxification, and reinforces the actions of the principal and deputy herbs. Its focus on the Lung and Liver channels enhances the formula’s ability to support immune function, promote metabolic balance, and encourage overall well-being.*
Turkey Tail / Cloud Mushroom (Trametes versicolor) – 12.5% of Formula
Description: Known as Yún Zhī in Classical Chinese Medicine (CCM), Turkey Tail has been traditionally used to support immune function and promote internal balance. It is associated with the Spleen (Pí) and Lung (Fèi) channels, where it is believed to regulate Qì, aid in fluid metabolism, and enhance the body’s natural defenses. Turkey Tail is also valued in detoxification practices, where it is used to clear dampness and heat, key factors in maintaining physiological equilibrium.*
Ethnobotanical Tradition: A staple in Chinese and Japanese herbal medicine, Turkey Tail has been used for centuries for its immune-modulating and detoxifying properties. Its rich concentration of polysaccharides and other bioactive compounds has made it a highly regarded mushroom for promoting long-term resilience and systemic support.*
Sourcing: Organically cultivated in Asia, our Turkey Tail is grown under conditions that maximize its potency, ensuring a high concentration of immune-supportive beta-glucans and polysaccharides.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Whole Mushroom
Role in Formula: As a Zuǒ Yào (Assistant) Herb, Turkey Tail reinforces immune function, aids in fluid metabolism, and strengthens the Spleen and Lung channels. Its role in managing dampness, clearing heat, and supporting the body's natural defense mechanisms makes it an integral component of the Twelve Rivers formula.*
Willow Bracket / Mesima (Phellinus igniarius) – 12.5% of Formula
Description: Known as Sāng Huáng in Classical Chinese Medicine (CCM), Willow Bracket has been traditionally used to support immune function and promote detoxification. It is closely associated with the Liver (Gān) and Kidney (Shèn) channels, where it is believed to aid in the clearance of toxins, regulate internal heat, and reinforce Yuán Qì), the body’s foundational energy. Willow Bracket is particularly valued for expelling dampness and reducing heat, key factors in maintaining physiological balance and systemic resilience.*
Ethnobotanical Tradition: Highly regarded in Chinese and Korean herbal traditions, Willow Bracket has long been used for immune support and detoxification. Its deep affinity with the Liver and Kidney channels has made it an important herb for maintaining internal equilibrium and supporting the body's ability to adapt to environmental stressors.*
Sourcing: Wild-harvested in Asia, our Willow Bracket is collected using traditional methods designed to preserve its full spectrum of beneficial compounds and enhance its detoxifying properties.
Extraction: Standardized to 30% polysaccharides through a dual-stage process combining hot water and alcohol extraction for full-spectrum bioavailability.
Parts Used: Fruiting Body
Role in Formula: As a Shǐ Yào (Envoy) Herb, Willow Bracket guides the actions of the formula toward the Liver and Kidney channels, enhancing detoxification, foundational energy, and systemic balance. It plays a critical role in coordinating the effects of the principal, deputy, and assistant herbs, ensuring the Twelve Rivers formula remains harmonized and effective.*
Our recommended method for using extract powders is simple: mix the powder with several ounces of warm to hot water, stir until dissolved, and drink promptly. To maximize absorption, take this product on an empty stomach, at least 30 minutes before consuming any other food or drink.
As a dietary supplement, adults take 2 grams (approximately 1 teaspoon) 1 – 2 times daily, preferably on an empty stomach. Please consult a qualified healthcare practitioner before use, especially if you have any medical conditions or are taking other medications. The dosage can be split into two servings—one in the morning and one in the evening.
Keep out of the reach of children. Do not use if safety seal is damaged or missing. Store at room temperature.
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* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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